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L-Lactate assay

Product Method Size Catalog Price Quantity
L-Lactate assay Colorimetric 16 x 6ml LC2389 $298.75
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  • Format
    Lyophilised
  • Assay Range
    0.165 - 19.7 mmol/l (1.49 - 178 mg/dl)
  • Working Stability 15-25 °C
    Working reagent stable for 2 weeks
  • Working Stability 2-8 °C
    Working reagent stable for 6 weeks
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Intended Use

For the quantitative in vitro determination of L-Lactate in plasma. This test is specific for L-Lactate only. This product is suitable for manual use and on the Rx Monza analyser.

Clinical Significance

L-Lactate is one of the raw materials of glucogenesis produced by the active skeletal muscle and erythrocytes and is metabolised by the liver. When tissue cannot be supplied with sufficient oxygen to support aerobic oxidation of the pyruvate and NADH produced in glycolysis, NAD+ is regenerated from NADH by reduction of pyruvate to lactate.

Increased concentration of lactate in the blood is thus an indicator of anaerobic metabolism ie. blood flow to the tissues decrease and oxygen delivery is insufficient. In cases of severe oxygen deprivation "Lactic Acidosis" may occur. L-Lactate may therefore be used as an indicator of severity of circulatory failure.

Available Applications

RX Monza