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Complement C3 assay

Product Method Size Catalog Price
Complement C3 assay Immunoturdidimetric R1 1 x 16.5ml, R2 1 x 5.4ml CM8348 POA
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  • Format
    Liquid ready-to-use
  • Assay Range
    5 - 540mg/dl
  • Working Stability 2-8 °C
    Stable to expiry
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Intended Use

A Complement C3 test system is a device intended for the quantitative in vitro determination of Complement C3 concentration in serum. This product is suitable for use on the RX daytona plus RX series analyser.

Clinical Significance

Complement is a complex biological system which works in conjunction with antibody and other factors to protect the body from invasion by pathogens. When activated by either the classical or alternative pathway Complement acts on biological membranes and may cause cell death. The human complement cascade consists of several distinct plasma proteins. Complement C3 and Complement C4 levels are important in determining inherited or acquired deficiencies. Conversely, levels may rise in a variety of inflammatory and necrotic disorders as part of the acute-phase plasma protein response

Principle

Sample is reacted with a buffer containing antibody specific for human complement C3 (B1 C-globulin; properdin factor A). The absorbance (340 nm) of the resulting turbid solution is proportional to the concentration of C3 in the sample. By constructing a standard curve from the absorbance of standards, C3 concentration of sample can be determined.

Available applications

RX Datyona+

RX Monaco

Abbott Architect

Hitachi 917/Mod P

Konelab 20i/30i/60i

Beckman Coulter AU Series