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Ammonia assay

Product Method Size Catalog Price Quantity
Ammonia assay Enzymatic UV R1 2x16, R2 2x6 AM8112 $132.00
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  • Format
    Liquid ready-to-use
  • Assay Range
    16.9 - 901μmol/l (0.278 - 14.8μg/ml)
  • Working Stability 2-8 °C
    Stable to expiry
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Intended Use

For the quantitative in vitro determination of Ammonia in plasma. This product is suitable for use on RX series analyser RX suzuka.

Clinical Significance

The major source of circulating ammonia is the GI tract. Under normal conditions, ammonia is metabolised to urea by liver enzymes. Several diseases, both inherited and acquired, cause elevated ammonia (hyperammonemia). The inherited deficiencies of urea cycle enzymes are the major cause of hyperammonemia in infants. The acquired hyperammonemia diseases are caused by liver disease, renal failure and Reye’s Syndrome. Elevated ammonia is toxic to the central nervous system.


Ammonia combines with -ketoglutarate and NADPH in the presence of glutamate dehydrogenase (GLDH) to yield glutamate and NADP+. The corresponding decrease in absorbance at 340 nm is proportional to the plasma ammonia concentration.

Available Applications

RX Suzuka